Serum Haptoglobin and Amyloid a Concentrations and Clinical Findings in Sheep with Peste Des Petits Ruminants
نویسندگان
چکیده
The changes in serum haptoglobin (Hp) and amyloid A (SAA) concentrations in sheep with peste des petits ruminants (PPR) were investigated. Additionally, the relationships between these acute phase proteins and clinical symptoms were studied. Twenty sheep showing PPR virus antibodies in c-ELISA and 10 sheep PPR virus negative were used as the experimental and control groups. In the clinical examination, typical clinical symptoms, such as fever, nasal catarrh, erosive stomatitis, gastroenteritis, and conjunctivitis were detected in all PPR affected animals. In addition, statistically significant differences were found in body temperature and respiratory and heart rates between experimental and control groups (P<0.001). SAA and Hp levels increased significantly (P<0.001) in PPR virus infected sheep in comparison with healthy animals. Consequently, the obtained data showed that although the acute phase proteins were not specific for the disease, serum Hp and SAA could be used as an indicator together with clinical findings in sheep with PPR.
منابع مشابه
Seroprevalence Study of Peste Des Petits Ruminants in Sheeps of Shabestar, Iran
Background Peste des petits ruminants (PPR) disease is one of the most important viral infections in sheep and goats that is caused by a morbillivirus from the paramixoviridae family, causing lesions in the gastrointestinal tract and respiratory tract. Methods In the present study, 250 blood samples were taken from the jugular vein of the apparently healthy and diseased sheep with common sympto...
متن کاملStudy of Peste Des Petits Ruminants (PPR) in Some Border Areas of Iran by Nested- PCR
In order to study on small ruminant rinderpest (PPR) in some border areas of Iran, totally 70 blood samples were taken via jugular vein from Kamyaran, Piranshahr, Lahijan, Ghorveh and Bilesavar district, in a tube with EDTA. The sampling was in the flocks located in Iran borders. The samples were sent near the ice container to laboratory. The blood samples included 28 goat and 42 sheep which to...
متن کاملCloning of fusion (F) protein gene of peste des petits ruminants virus (PPRV) in secretory Pichia pastoris vector
With advent and development of DNA recombinant technology and advantages of p. pastoris expression system, fusion (F) protein of PPRV expression, because of effective immunodominant role could be an appropriate candidate for production of recombinant vaccine against PPR disease. In this study, F gene of PPRV Nigeria 75/1 strain (1637 bp) was amplified using RT-PCR and purified. It was then cl...
متن کاملReviewon Peste Des Petits Ruminants (PPR)
A Peste des Petits Ruminant is a contagious disease affecting goats and sheep in Sub-Saharan Africa extending to the Arabian Peninsula, Middle Eastern countries and India. It is a list a disease that is caused by the Morbillivirus (family Paramyxoviridae). Peste des Petits Ruminant Virusis related to Rinderpest virus which it shares common antigenic determinant. Goats are more susceptible to Pe...
متن کامل